常然然，副教授，博士生导师，青岛大学特聘教授。2021年底毕业于江南大学获食品科学博士学位，2022年1月入职于青岛大学医学院公共卫生学院，主要从事谷物食品加工与人类肠道营养和健康相关的科研教学工作。先后主持国家自然科学基金项目、中国科协青年人才托举工程项目、中国博士后科学基金面上项目、青岛大学人才引进科研启动项目等。在国内外食品与营养相关期刊上以第一/通讯作者发表SCI论文25篇，其中1区19篇，高被引1篇，获授权国家发明专利4件。兼任中国营养学会功能性碳水化合物物与健康产业分会常务委员、中国营养学会海洋食品营养与健康分会秘书等。
一、主要研究方向
1. 谷物资源精深加工与利用（低GI谷物和全谷物食品）
2. 抗性淀粉对防治2型糖尿病、肥胖、肠道疾病等功效和机制研究
3. 人类肠道营养与健康（谷物食品和海洋资源食品）
4. 精准营养的多糖纳米营养递送体系构建及功效研究
二、代表性科研成果
1）学术论文
1.Jie Liu, Yanchen Meng, Aiguo Ma, Ranran Chang*. Digestion and fermentation of bionic grain-resistant corn starch and its effects on glucose response in mice. npj Science of Food, 2026, 10, 1-15. (1区, IF =7.8)
2.Yuan Chen#, Lili Fu#, Yanyan Wang, Ranran Chang*, Aiguo Ma. Cholesterol-lowering effects of phytosterol combined with phosphatidylcholine and their mechanism of action in hypercholesterolemic rats. Food & Function, 2025, 16, 7858-7879. (2区, IF=5.4)
3.Kunjie Xu, Yuan Chen, Ranran Chang*, and Aiguo Ma. Konjac glucomannan-embedded corn starch-derived type 1 resistant starch: Physicochemical properties, in vitro digestibility and fermentation characteristics, and in vivo glucose response in mice. International Journal of Biological Macromolecules, 2025, 301, 140372. (2区, IF=8.5)
4.Jie Liu#, Zihang Wang#, Chenchen Hu, Jingxuan Xu, Ranran Chang*. Manipulation of the structure of type 4 resistant starch using cross-linking and acylation treatment and its diverse influence on digestion and in vitro fermentation characteristics. Current Research in Food Science, 2025, 11, 101125. (1区, IF=7.7)
5.Kunjie Xu, Fangfei Ji, Yuexin Yang, Ranran Chang*, and Aiguo Ma. In-Depth Investigation of the Mechanisms Underlying Recrystallized Resistant Starch-Induced Amelioration of Insulin Resistance in T2DM Mice via Liver Metabolomics Integrated with Colon Transcriptomics. ACS Food Science & Technology, 2024, 4, 3182-3194.
6.Ranran Chang*, Jie Liu, Fangfei Ji, Lili Fu, Kunjie Xu, Yuexin Yang, Aiguo Ma. Hypoglycemic effect of recrystallized resistant starch on high-fat diet- and streptozotocin-induced type 2 diabetic mice via gut microbiota modulation. International Journal of Biological Macromolecules, 2024, 261, 129812. (1区, IF =7.7)
7.Ranran Chang, Zihang Wang, Lili Fu, Chuanjing Chen, Kunjie Xu, Aiguo Ma, Yaoqi Tian*. Recrystallized resistant starch by encapsulation with konjac glucomannan: structural changes, digestibility, and its effect on glucose response and short-term satiety in mice. Food Chemistry. 2024, 442, 138379. (1区, IF =9.8)
8.Ranran Chang*, Kunjie Xu, Rao Zhang, Zhengyu Jin, Ma Aiguo. A combined recrystallization and acetylation strategy for resistant starch with enhanced thermal stability and excellent short-chain fatty acid production. Food Chemistry. 2024, 430, 136970. (1区, IF =9.8)
9.Ranran Chang, Fan Wang, Jiating Huang, Zhengyu Jin, Yaoqi Tian*. Recrystallized resistant starch: Structural changes in the stomach, duodenum, and ileum and the impact on blood glucose and intestinal microbiome in mice. Journal of Agricultural and Food Chemistry. 2023, 71, 12080-12093. (1区, IF=5.9)
10.Ranran Chang, Zhengyu Jin, Yaoqi Tian*. Insights into the structural, morphological, and thermal property changes in simulated digestion and fermentability of four resistant starches from high amylose maize starch. Food Hydrocolloids. 2023, 142, 108770. (1区, IF=10.7)
2）发明专利
1. 一种抗消化淀粉的制备方法, 田耀旗, 金征宇, 常然然, 等. 授权CN111264867 B
2. 葡萄糖响应型的伴刀豆球蛋白‑淀粉纳米颗粒的制备方法及其应用, 孙庆杰, 熊柳, 常然然. 授权CN106937948 B
3. 双亲性辛烯基琥珀酸短直链淀粉纳米颗粒及其制备方法, 孙庆杰, 熊柳, 常然然, 等. 授权CN106580879 B
4. 一种乳酸链球菌素肽纳米颗粒及其制备方法和应用，孙庆杰, 熊柳, 常然然, 等. 授权CN 107668474B
三、主要科研项目
1. 中国科学技术协会第十届青年人才托举工程项目，2024-2026QNRC001，2024-2026年，主持，在研。
2. 国家自然科学基金青年项目，2024/01-2026/12，主持，在研。
3. 中国博士后科学基金面上项目，2023M730451，2023/06-2025/06，主持。
四、联系方式
E-mail：18254597115@163.com
