季晓亚,女,1992年生,山东枣庄人,2020年6月毕业于中国科学院生态环境研究中心,获得环境科学博士学位。现为青岛大学公共卫生学院助理教授,青年卓越人才。
一、主要研究方向
大气细颗粒物的吸入毒理和神经毒理
二、代表性科研成果
1. Xiaoya Ji#, Rui Liu#, Jiajun Guo, Yanting Li, et al. Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors. Science of the Total Environment. 2022, 821: 153456.
2. Xiaoya Ji, Na Li, Mei Ma, Kaifeng Rao, et al. Comparison of the mechanisms of estrogen disrupting effects between triphenyl phosphate (TPhP) and tris(1,3-dichloro-2-propyl) phosphate (TDCIPP). Ecotoxicology and Environmental Safety. 2022, 229: 113069.
3. Xiaoya Ji, Na Li, Mei Ma, Kaifeng Rao, et al. Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways. Environmental Pollution. 2020, 264: 114747.
4. Xiaoya Ji, Na Li, Mei Ma, Kaifeng Rao, et al. In vitro estrogen-disrupting effects of organophosphate flame retardants. Science of the Total Environment. 2020, 727: 138484.
5. Xiaoya Ji, Na Li, Rong Yang, Kaifeng Rao, et al. The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as a novel molecular initiating event of 4-n-nonylphenol in estrogen receptor α-mediated pathways. Ecotoxicology and Environmental Safety. 2020, 189: 109958.
6. Xiaoya Ji, Na Li, Shengwu Yuan, Xiaohong Zhou, et al. A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro. Ecotoxicology and Environmental Safety. 2019. 175: 208-214.
7. 季晓亚, 李娜, 等. 环境雌激素生物效应的作用机制研究进展. 生态毒理学报. 2017, 12, (01): 38-51.
8. 季晓亚, 杨明嘉, 等. 酵母双杂交技术构建稀有鮈鲫不同雌激素受体亚型的重组荧光酵母. 生态毒理学报. 2019, 14(05): 108-113.
9. Shengwu Yuan, Xiaoya Ji, Mei Ma, et al. Comparative toxicity study of a novel non-ionic surfactant, vanillin ethoxylates, and nonylphenol ethoxylates in Chinese hamster ovary cells in vitro. Journal of Environmental Sciences-China, 2019, 82: 70-81.
10. Shengwu Yuan, Chao Huang, Xiaoya Ji, Mei Ma, et al. Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene. Ecotoxicology and Environmental Safety, 2018, 160:1-9.
11. Chao Huang, Na Li, Shengwu Yuan, Xiaoya Ji, et al. Aryl- and alkyl-phosphorus-containing flame retardants induced mitochondrial impairment and cell death in Chinese hamster ovary (CHO-k1) cells. Environmental Pollution. 2017, 230:775-786.
三、主要科研项目
应激颗粒核心组分G3BP1在柴油机尾气致气道上皮稳态失衡中的作用机制研究,国家自然科学青年基金,30万,在研,2023.01-2025.12,主持
柴油机尾气颗粒物通过Ryk介导的典型Wnt途径导致气道粘液过度分泌的毒性机制研究,山东省自然科学青年基金,15万,在研,2022.01-2024.12,主持
四、联系方式
E-mail:jxya1992@163.com或jxya@qdu.edu.cn