王伟静，医学博士，流行病与卫生统计学系讲师。任青岛市医学会循证医学分会委员, 山东预防医学会卫生事业管理分会委员。长期从事慢性非传染病流行病学、遗传流行病学、循证医学研究。讲授《流行病学》、《临床流行病学》、《现场流行病学》等课程。主持山东省自然科学基金项目1项、中国博士后科学基金项目1项。以第一/通讯作者发表SCI收录论文17篇。2017年赴南丹麦大学交流学习半年。
一、主要研究方向
慢性非传染病流行病学、遗传流行病学
二、代表性科研成果
(1) Wang W, Yao J, Li W, Wu Y, Duan H, Xu C, Tian X, Li S, Tan Q, Zhang D. Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure. Clin Epigenetics. 2023 Mar 3;15(1):38.
(2) Wang W, Li W, Jiang W, Lin H, Wu Y, Wen Y, Xu C, Tian X, Li S, Tan Q, Zhang D. Genome-wide DNA methylation analysis of cognitive function in middle and old-aged Chinese monozygotic twins. J Psychiatr Res. 2021 Apr;136:571-580.
(3) Wang W, Li W, Wu Y, Tian X, Duan H, Li S, Tan Q, Zhang D. Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression. Transl Psychiatry. 2021 Aug 2;11(1):416.
(4) Wang W*, Yao W, Tan Q, Li S, Duan H, Tian X, Xu C, Zhang D. Identification of key DNA methylation changes on fasting plasma glucose: a genome-wide DNA methylation analysis in Chinese monozygotic twins. Diabetol Metab Syndr. 2023 Jul 17;15(1):159.
(5) Wang W, Jiang W, Hou L, Duan H, Wu Y, Xu C, Tan Q, Li S, Zhang D. Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI. BMC Genomics. 2017 Nov 13;18(1):872.
(6) Wang W*, Li W, Duan H, Xu C, Tian X, Li S, Tan Q, Zhang D. Mediation by DNA methylation on the association of BMI and serum uric acid in Chinese monozygotic twins. Gene. 2023 Jan 20;850:146957.
(7) Wang A, Wang N, Zhang D, Wen J, Wang W*. Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone. Nutrients. 2023 May 30;15(11):2549.
(8) Ge L, Liu J, Kang X, Wang W*, Zhang D*. Association of serum individual and mixed aldehydes with depressive symptoms in the general population: A machine learning study. J Affect Disord. 2024 Jan 15;345:8-17.
(9) Weijing Wang, Wenjie Jiang, Lin Hou, Haiping Duan, Yili Wu, Chunsheng Xu, Qihua Tan, Shuxia Li and Dongfeng Zhang. Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI. BMC Genomics. 2017, 18(1): 872.
(10) Weijing Wang, Dongfeng Zhang, Chunsheng Xu, Yili Wu, Haiping Duan, Shuxia Li and Qihua Tan. Heritability and genome-wide association analyses of serum uric acid in middle and old-aged Chinese twins. Front Endocrinol. 2018, 9:75.
三、主要科研项目
1.全基因组DNA甲基化与中老年高尿酸血症关系的同卵双生子研究，山东省自然科学基金，14万元，2021-2023，主持
2.环境因素、钙离子信号通路相关基因多态性和DNA甲基化与老年人认知功能关系的因果效应研究，8万元，中国博士后科学基金，2021-2023，主持
3.内皮素信号通路基因 DNA 甲基化与老年人认知功能的关联研究，青岛市博士后应用研究项目，5万元，2021-2023，主持
四、主要科学技术奖励
1. 生命早期饥饿暴露诱导TLR4通路甲基化与代谢综合征，山东省科技创新成果奖，2024年1月，第伍位
五、联系方式
E-mail：wangwj793@126.com
