常然然,工学博士,副教授,硕士研究生导师,现为青岛大学特聘教授第五层次。
2021年12月于江南大学获食品科学博士学位,2022年1月入职于青岛大学医学部公共卫生学院,主要从事谷物食品加工与人类肠道营养和健康相关的科研教学工作。2022年6月-至今于大连工业大学-国家海洋食品工程技术研究中心从事海洋食品营养健康相关的博士后工作。目前累计在Journal of Agricultural and Food Chemistry、Food Chemistry、Food Hydrocolloids、Ultrasonics Sonochemistry等国际期刊发表SCI论文30余篇,其中第一或通讯作者发表20余篇。授权国家发明专利4件。主持国家级科研项目2项,包括国家自然基金项目和中国博士后科学基金面上项目,青岛大学人才引进科研启动项目1项。
一、主要研究方向
1. 谷物资源精深加工与利用
2. 抗性淀粉对防治2型糖尿病、肥胖、肠道疾病等功效和机制研究
3. 人类肠道营养与健康(谷物食品和海洋资源食品)
4. 精准营养的多糖纳米营养递送体系构建及功效研究
二、代表性科研成果
1)学术论文
1.Ranran Chang*, Jie Liu, Fangfei Ji, Lili Fu, Kunjie Xu, Yuexin Yang, Aiguo Ma. Hypoglycemic effect of recrystallized resistant starch on high-fat diet- and streptozotocin-induced type 2 diabetic mice via gut microbiota modulation. International Journal of Biological Macromolecules, 2024, 261, 129812.
2.Ranran Chang, Zihang Wang, Lili Fu, Chuanjing Chen, Kunjie Xu, Aiguo Ma, Yaoqi Tian*. Recrystallized resistant starch by encapsulation with konjac glucomannan: structural changes, digestibility, and its effect on glucose response and short-term satiety in mice. Food Chemistry. 2024, 442, 138379.
3.Ranran Chang*, Kunjie Xu, Rao Zhang, Zhengyu Jin, Ma Aiguo. A combined recrystallization and acetylation strategy for resistant starch with enhanced thermal stability and excellent short-chain fatty acid production. Food Chemistry. 2024, 430, 136970.
4.Ranran Chang, Fan Wang, Jiating Huang, Zhengyu Jin, Yaoqi Tian*. Recrystallized resistant starch: Structural changes in the stomach, duodenum, and ileum and the impact on blood glucose and intestinal microbiome in mice. Journal of Agricultural and Food Chemistry. 2023, 71, 12080-12093.
5.Ranran Chang, Zhengyu Jin, Yaoqi Tian*. Insights into the structural, morphological, and thermal property changes in simulated digestion and fermentability of four resistant starches from high amylose maize starch. Food Hydrocolloids. 2023, 142, 108770.
6.Ranran Chang, Zhengyu Jin, Hao Lu, Lizhong Qiu, Chunrui Sun, Yaoqi Tian*. Type III resistant starch prepared from debranched starch: Structural changes under simulated saliva, gastric, and intestinal conditions and the impact on short-chain fatty acid production. Journal of Agricultural and Food Chemistry. 2021, 69, 2595−2602.
7.Ranran Chang, Hao Lu, Xiliang Bian, Yaoqi Tian*, Zhengyu Jin. Ultrasound assisted annealing production of resistant starches type 3 from fractionated debranched starch: Structural characterization and in-vitro digestibility. Food Hydrocolloids. 2021, 110, 106141.
8.Ranran Chang, Yaoqi Tian, Hao Lu, Chunrui Sun, Zhengyu Jin*. Effects of fractionation and heat-moisture treatment on structural changes and digestibility of debranched waxy maize starch. Food Hydrocolloids. 2020, 101, 105488.
9.Ranran Chang, Man Li, Shengju Ge, Jie Yang, Qingjie Sun*, Liu Xiong*. Glucose-responsive biopolymer nanoparticles prepared by co-assembly of concanavalin A and amylopectin for insulin delivery. Industrial Crops and Products. 2018, 112, 98-104.
10.Ranran Chang, Jie Yang, Shengju Ge, Mei Zhao, Caifeng Liang, Liu Xiong, Qingjie Sun. Synthesis and self-assembly of octenyl succinic anhydride modified short glucan chains based amphiphilic biopolymer: micelles, ultrasmall micelles, vesicles, and lutein encapsulation/release. Food Hydrocolloids. 2017, 67, 14-26.
2)发明专利
1. 一种抗消化淀粉的制备方法, 田耀旗, 金征宇, 常然然, 等. 授权CN111264867 B
2. 葡萄糖响应型的伴刀豆球蛋白‑淀粉纳米颗粒的制备方法及其应用, 孙庆杰, 熊柳, 常然然. 授权CN106937948 B
3. 双亲性辛烯基琥珀酸短直链淀粉纳米颗粒及其制备方法, 孙庆杰, 熊柳, 常然然, 等. 授权CN106580879 B
4. 一种乳酸链球菌素肽纳米颗粒及其制备方法和应用,孙庆杰, 熊柳, 常然然, 等. 授权CN 107668474B
三、主要科研项目
1. A-型结晶抗性淀粉调控肠道细菌协作产丁酸机制研究,国家自然科学基金青年项目, 30万元,2024/01-2026/12,主持
2. 中国博士后科学基金面上项目,2023M730451,8万元,2023/06-2025/06,主持
四、联系方式
E-mail:18254597115@163.com